It appears that support for "legacy" system calls has vanished. This may affect anything written for XP or earlier, or things that might be supporting XP or earlier calls. There have been reports of stuff supposedly written for Vista breaking, because it was using older calls without the author realizing it. Microsoft sent out a "transition guide" to it's super expensive membership developers and it has slowly trickled down. But many folks who have written what they thought was "portable" code are learning otherwise. And a rebuild may not even help, it may take a rewrite.
exception code 0xc14b - call not handled. kernel exception in user mode this one kills the program mid stream. the kernel exception used to actually occur in kernel mode and you'd see a BSOD.
there are two other exceptions, one of which will make things "just not work" and the other will sometimes, but not always, and not predictably, produce "interesting" results.