Check out this awesome Kickstarter project by the same guys that worked with Ladyada to develop the Drawdio. Take a MaKey MaKey controller, connect up some alligator clips to just about anything conductive, and interact with your computer and the internet.
Alligator Clip two objects to the MaKey MaKey board. For example, you and an apple.
When you touch the apple, you make a connection, and MaKey MaKey sends the computer a keyboard message. The computer just thinks MaKey MaKey is a regular keyboard (or mouse). Therefore it works with all programs and webpages, because all programs and webpages take keyboard and mouse input.
Make + Key = MaKey MaKey!